Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

Grants

Funding Acknowledgements

N.M.W was supported by a National Health and Medical Research Council Early Career Fellowship (APP1104818). E.S. was supported by the European Commission within the framework of the Erasmus-Western Balkans (ERAWEB). M.H was supported by a National Health and Medical Research Council Practitioner Fellowship (APP1058935). F.R. was supported by the Netherlands Scientific Organization (NWO) and ZonMW Project number: NWO/ZONMW-VIDI-016-136-367. S.E.M was supported by a National Health and Medical Research Council Senior Research Fellowship (APP1103623). D.M.E was supported by an Australian Research Council Future Fellowship (FT130101709) and an MRC programme grant (MC_UU_12013/4). ALSPAC: GWAS data was generated by Sample Logistics and Genotyping Facilities at the Wellcome Trust Sanger Institute and LabCorp (Laboratory Corporation of America) using support from 23andMe. The UK Medical Research Council and the Wellcome Trust (grant reference: 102215/2/13/2) and the University of Bristol provide core support for ALSPAC. This work is supported by a Medical Research Council program grant (grant reference: MC_UU_12013/4 to D.M.E). The androgen receptor CAG repeat data was generated with funding from the Medical Research Council (grant reference: G0500953 to Barbara Maughan). This publication is the work of the authors, and D.M.E will serve as guarantor for the contents of this paper. Generation R Study: The general design of Generation R Study was made possible by financial support from the Erasmus Medical Center, Rotterdam, the Erasmus University Rotterdam, the Netherlands Organization for Health Research and Development (ZonMw), the Netherlands Organisation for Scientific Research (NWO), the Ministry of Health, Welfare and Sport and the Ministry of Youth and Families. The musculoskeletal research of the Generation R Study was partly supported by the European Commission grant HEALTH-F2-2008-201865-GEFOS. Additionally, the Netherlands Organization for Health Research and Development supported authors of this manuscript (ZonMw 907.00303, ZonMw 916.10159, ZonMw VIDI 016.136.361 to V.W.J. and ZonMw VIDI 016.136.367 to F.R.). This project also received funding from the European Union's Horizon 2020 research and innovation programme under the following grant agreements: No. 633595 (DynaHEALTH) and No. 733206 (LIFECYCLE), and from the European Research Council (ERC Consolidator Grant, ERC-2014-CoG-648916 to V.W.J.). QIMR: The QIMR studies were supported by funding from the Australian National Health and Medical Research Council (grant numbers: 241944, 339462, 389927, 389875, 389891, 389892, 389938, 443036, 442915, 442981, 496739, 552485 and 552498, and most recently 1049894) and the Australian Research Council (grant numbers: A7960034, A79906588, A79801419, DP0212016 and DP0343921). The Rotterdam Study: The GWAS datasets were supported by the Netherlands Organisation of Scientific Research NWO Investments (no. 175.010.2005.011, 911-03-012), the Genetic Laboratory of the Department of Internal Medicine, Erasmus MC, the Research Institute for Diseases in the Elderly (014-93-015; RIDE2), the Netherlands Genomics Initiative (NGI)/Netherlands Organisation for Scientific Research (NWO) Netherlands Consortium for Healthy Aging (NCHA), project no. 050-060-810. Dr Fernando Rivadeneira received an additional grant from the Netherlands Organization for Health Research and Development ZonMw VIDI 016.136.367. The Rotterdam Study was funded by Erasmus Medical Center and Erasmus University, Rotterdam, Netherlands Organization for the Health Research and Development (ZonMw), the Research Institute for Diseases in the Elderly (RIDE), the Ministry of Education, Culture and Science, the Ministry for Health, Welfare and Sports, the European Commission (DG XII) and the Municipality of Rotterdam. Twins UK: The study was funded by the Wellcome Trust (Ref: 105022/Z/14/Z); European Community's Seventh Framework Programme (FP7/2007-2013). The study also receives support from the National Institute for Health Research (NIHR)-funded BioResource, Clinical Research Facility and Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust in partnership with King's College London. SNP Genotyping was performed by The Wellcome Trust Sanger Institute and National Eye Institute via NIH/CIDR. Raine: The following Institutions provide funding for Core Management of the Raine Study: The University of Western Australia (UWA), Raine Medical Research Foundation, UWA Faculty of Medicine, Dentistry and Health Sciences, The Telethon Institute for Child Health Research, Curtin University, Edith Cowan University and Women and Infants Research Foundation. This study was supported by project grants from the National Health and Medical Research Council of Australia (grant numbers: 403981, 003209 and 1021105; http://www.nhmrc.gov.au; date last accessed April 13, 2018) and the Canadian Institutes of Health Research (grant number: MOP-82893; http://www.cihrirsc.gc.ca/e/193.html; date last accessed April 13, 2018). This work was also supported by resources provided by the Pawsey Supercomputing Centre with funding from the Australian Government and the Government of Western Australia. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.